Williamson Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it tries to repair itself before the harm was done. Apple Country Chiropractic is never shocked at how the body takes care of itself! Apple Country Chiropractic sees its Williamson chiropractic care as the body’s partner in healing especially when there is spine pain. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is proving value by interrupting the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process during which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin increased autophagy and lessened the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin prevents intervertebral disc degeneration by promoting autophagy. (3) Wow. Apple Country Chiropractic is encouraged by this research to see just how well melatonin can perform for Williamson back pain linked to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is quite a common condition seen at Apple Country Chiropractic making positive news like this quite rousing. A new study explained how melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin reduced the inflammatory cell collection and decreased the release of connected inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin disrupted the IL-1B feedback loop, researchers postulated that melatonin may support the restoration process of intervertebral discs after damage has already been done. (1) Apple Country Chiropractic will keep following the new research regarding the role inflammation plays in Williamson disc degeneration and melatonin’s role in tackling it.

INFLAMMATION AND MELATONIN

The importance of melatonin in helping to slow or stop painful conditions due to inflammation is growing. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other things is quite apropos. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific influence on inflammation and disc degeneration is most interesting to Apple Country Chiropractic and our Williamson back pain patients.

CONTACT Apple Country Chiropractic

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management addresses disc degeneration for relief of chronic low back pain in her patient.

Schedule your Williamson chiropractic appointment with Apple Country Chiropractic today. We can talk about the role inflammation plays in your back pain experience and how melatonin may address the related disc degeneration.

 
Apple Country Chiropractic shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."